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KILLER CELLS, NATURAL
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DeCS
Descriptor
English
:
Killer Cells, Natural
Descriptor
Spanish
:
Células Asesinas Naturales
Descriptor
Portuguese
:
Células Matadoras Naturais
Synonyms
English
:
NK Cells
Natural Killer Cells
Tree Number:
A11.118.637.555.567.537
A15.145.229.637.555.567.537
A15.382.490.555.567.537
Definition
English
:
Bone marrow-derived
lymphocytes
that possess cytotoxic properties, classically directed against transformed and virus-infected
cells
. Unlike T
CELLS
; and B
CELLS
; NK
CELLS
are not antigen specific. The cytotoxicity of natural killer
cells
is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of
T-LYMPHOCYTES
referred to as NATURAL KILLER T
CELLS
shares some of the properties of this cell type.
Indexing Annotation
English
:
do not confuse with
NATURAL KILLER T-CELLS
; if subpopulations are discussed, coordinate IM with
LYMPHOCYTE SUBSETS
(IM)
See Related
English
:
Receptors, Natural Killer Cell
History Note
English
:
1983
Allowable Qualifiers
English
:
CH
chemistry
CL
classification
CY
cytology
DE
drug effects
EN
enzymology
IM
immunology
ME
metabolism
MI
microbiology
PS
parasitology
PA
pathology
PH
physiology
RE
radiation effects
RA
radiography
RI
radionuclide imaging
SE
secretion
TR
transplantation
US
ultrasonography
UL
ultrastructure
VI
virology
Record Number:
23295
Unique Identifier:
D007694
Occurrence in VHL
:
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